Invasive Aspergillosis-on-Chip: A Quantitative Treatment Study of Human Aspergillus fumigatus Infection

T N M Hoang, Z Cseresnyés, S Hartung, M Blickensdorf, C Saffer B, K Rennert, A S Mosig, M von Lilienfeld-Toal#, M T Figge# (2022). Invasive Aspergillosis-on-Chip: A Quantitative Treatment Study of Human Aspergillus fumigatus Infection. Biomaterials.

This paper combines a microfluidic organ-on-chip model with a computational, quantitative image-analysis pipeline to study invasive aspergillosis in a human-relevant in vitro system, enabling controlled, quantitative treatment studies of Aspergillus fumigatus infection outside a living host.